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Shit might get weird

Shit might get weirdShit might get weirdShit might get weird

Healthy thoughts - damn good Preventitve maintenance plan

Never underestimate the power of a single thought.

" Daughter, your faith has made you well; go in peace, and be healed of your disease.” 

 Matthew 9:22 / Mark 5:34 / Luke 8:48 


 “According to your faith, let it be done to you.” 

 Matthew 9:29


 “Woman, great is your faith! Be it done for you as you desire.” 

 Matthew 15:28


 “Go; *your faith has made you well.” 

 Mark 10:52 / Luke 18:42 


 “Rise and go your way; *your faith has made you well.” 

 Luke 17:19


 “Jesus answered them, ‘Is it not written in your Law, “I said, you are gods”?’” 

 John 10:34 (ESV) 

Evidence of how awesome you are! Act accordingly :)

Placebo Surgery – Yes, it’s happened

 knee Surgery Study (2002 – Dr. Bruce Moseley)

• Patients with severe knee pain (osteoarthritis) were split into 3 groups:

1. Real arthroscopic surgery

2. Only a saline wash of the knee

3. Placebo surgery: The patient was sedated, cut open, but no real procedure was done.

• Results: The placebo group reported just as much pain relief as those who had the real surgery.

• Published in the New England Journal of Medicine. 

Parkinson’s Disease – Dopamine spike with fake treatment

  • Patients with Parkinson’s were given a placebo saline injection they were told was an expensive drug.

• Their brains released more dopamine as if they’d gotten actual medication.

• Shows the brain chemically responds to belief. 

Hotel Maids Burn More Calories When They Think They’re Exercising


• A study told one group of hotel maids that their daily work (cleaning, making beds) counted as exercise.

• The other group wasn’t told anything.

• After a few weeks, the “informed” group lost more weight, lowered blood pressure, and improved body fat percentage—even though their routines didn’t change.

• Their belief about the work changed their bodies.

https://pubmed.ncbi.nlm.nih.gov/17425538/


https://mbl.stanford.edu/sites/g/files/sbiybj26571/files/media/file/2007_exercise_mindset_crumlanger_psych_sci.pdf?utm_source=chatgpt.com

Mind over Milkshake

        • Participants were given a milkshake labeled either “120-calorie diet shake” or “620-calorie indulgent shake.”

• Both shakes were actually the same.

• Those who believed they drank the indulgent one had a greater drop in ghrelin, the hunger hormone—their bodies reacted as if they ate more.


https://pubmed.ncbi.nlm.nih.gov/21574706/?utm_source=chatgpt.com

The Teacher Expectation Study (Rosenthal & Jacobson)

• Teachers were told certain (random) students were “late bloomers” who were about to show huge academic growth.
• By the end of the year, those students did outperform others—even though they had no real difference in ability.
• Teachers’ belief in them changed how they treated them, which then shaped the students’ behavior.

Pygmalion in the Classroom: Teacher Expectation and Pupils' Intellectual Development by Robert Rosenthal and Lenore Jacobson

Stereotype Threat and Women's Math Performance.

Stereotype Threat
1999 research conducted by Steven J. Spencer, Claude M. Steele, and Diane M. Quinn, 

• Impact of Stereotype Activation: When women were informed that a math test had previously shown gender differences favoring men, they performed worse than their male counterparts. Conversely, when told the test showed no gender differences, women's performance matched that of men.​
• But when no stereotype is mentioned, their scores are equal.
• Expectation influences performance, not ability.

https://www.hendrix.edu/uploadedFiles/Academics/Faculty_Resources/2016_FFC/

Stereotype Threat and the Intellectual Test Performance of African Americans

 Researchers: Claude M. Steele and Joshua Aronson
•  Black college students underperformed on verbal tests when told the test measured intelligence.
•  When the same test was described as non-diagnostic (not measuring ability), the performance gap between Black and white students decreased.
•  The difference in performance was attributed to stereotype threat — the anxiety or concern about confirming negative stereotypes about one's group.
•  Demonstrated that psychological factors (like stereotype awareness) can significantly influence test performance. Our transportation solutions can help you create a more efficient and sustainable transportation system. From electric vehicles to smart traffic management systems, we can help you reduce congestion and improve mobility.

•  Published in: Journal of Personality and Social Psychology

Fake Wine Tastes Better

 People were told they were drinking a $90 bottle of wine, but it was actually a $10 bottle.

•Brain scans showed their pleasure centers lit up more, and they genuinely liked the wine more.

•Belief shaped sensory experience.


Caltech and Stanford University

https://www.caltech.edu/about/news/wine-study-shows-price-influences-perception-1374?utm_source=chatgpt.com 


Athletes & Performance Boosts

 • Some runners or weightlifters perform measurably better when told they’re getting a performance-enhancing supplement (sugar pill), especially if it’s hyped up.

• Magnitude of Effects: A systematic review reported that placebo effects in sports performance have a moderate to large impact (effect size d = 0.67). Interestingly, nocebo effects—negative outcomes due to negative expectations—were found to be even more substantial (effect size d = 1.20), highlighting the powerful role of psychological factors in athletic performance. If customers can’t find it, it doesn’t exist. Clearly list and describe the services you offer. Also, be sure to showcase a premium service.

Vision Improvement through Belief

 •In one study, people pretending to be Air Force pilots in a simulator actually performed better on eye tests—just because they believed they were in a role that required sharper vision.

https://pubmed.ncbi.nlm.nih.gov/20483844/?utm_source=chatgpt.com  

Mindset About Aging

 •People with positive beliefs about aging tend to live 7.5 years longer on average than those with negative beliefs.
•This effect held even when controlling for health, income, and age.

https://pubmed.ncbi.nlm.nih.gov/12150226/?utm_source=chatgpt.com 

Anecdote about pain without injury

 

  •  The British Medical Journal (BMJ) published a report in 1995 about a 29-year-old builder who experienced severe pain after jumping onto a 15 cm nail that pierced his boot. 
  • He was sedated due to the extreme pain, and the nail was carefully removed. 
  • However, upon removing his boot, doctors discovered that the nail had passed between his toes without causing any injury to his foot.    

https://www.painscience.com/biblio/source-of-boot-nail-guy-a-popular-medical-anecdote-about-pain-without-injury-nociception.html?utm_source=chatgpt.com


https://www.psychologytoday.com/us/blog/pain-explained/201911/a-tale-of-two-nails-what-changes-pain?utm_source=chatgpt.com


https://matrixtherapypt.com/pain-part-ii-curious-inconsistencies-pain/?utm_source=chatgpt.com

Placebo effect

Placebo Surgery – Yes, it’s happened

 Knee Surgery Study (2002 – Dr. Bruce Moseley)

• Patients with severe knee pain (osteoarthritis) were split into 3 groups:

1. Real arthroscopic surgery

2. Only a saline wash of the knee

3. Placebo surgery: The patient was sedated, cut open, but no real procedure was done.

• Results: The placebo group reported just as much pain relief as those who had the real surgery.

• Published in the New England Journal of Medicine.


Parkinson’s Disease – Dopamine spike with fake treatment

 • Patients with Parkinson’s were given a placebo saline injection they were told was an expensive drug.

• Their brains released more dopamine as if they’d gotten actual medication.

• Shows the brain chemically responds to belief. 

Fake Oxygen for Athletes

 Cyclists were told they were breathing oxygen-enriched air to boost endurance.

• It was just normal air.

• They still performed significantly better, thinking they had an edge. 

“Fake” Antidepressants vs Real Ones

 In some studies, placebos were nearly as effective as SSRIs (like Prozac), especially in mild to moderate depression.

• The belief in the treatment made a real difference in mood and outlook. 

Color & Brand Influence

 

• Red and orange pills work better as “stimulants” in tests, even when they’re sugar pills.

• Blue pills were more effective as sedatives.

• Branded placebo pills often outperform generic-looking ones—just because they “feel” more legit. 

Open-label Placebos

  • In some trials, people are told they’re taking a placebo, and it still works.
  •  This has been shown with conditions like IBS and chronic pain.

Sham Pacemakers and Implanted Devices

 • In some heart failure trials, patients were implanted with a sham pacemaker or defibrillator—devices that looked and felt real but weren’t actually activated.

• Many reported improved symptoms, less fatigue, and better energy just from believing they had a life-saving device in them. 

Fake Acupuncture

 

In multiple trials, sham acupuncture (where the needles don’t even penetrate the skin or are inserted in the “wrong” spots) produced as much or more pain relief than real acupuncture.

• Belief in the ritual of the treatment played a huge role. 

Placebo Response in Surgery for Angina (1950s!)

 Surgeons tied off arteries to the chest wall, believing it would increase blood flow to the heart (it didn’t).

• Some patients underwent a sham procedure—incision only, no ligation.

• Both groups reported improved angina symptoms.

• Once placebo was revealed, that whole surgery was abandoned.

Fake Alcohol & Drunkenness

• People who are given non-alcoholic drinks but are told they’re drinking real alcohol can still act drunk—slurred speech, clumsiness, and even memory issues.

• Shows how expectation alone can recreate the effects of a drug. 

Immune System Activation

• People who are given non-alcoholic drinks but are told they’re drinking real alcohol can still act drunk—slurred speech, clumsiness, and even memory issues.

• Shows how expectation alone can recreate the effects of a drug. 

Sham Brain Surgeries for Parkinson’s

•  In multiple studies, surgeons implanted inert material or did mock brain surgeries, telling patients they were getting experimental brain implants.

• Some of these patients had real improvements in tremors and motor function, even though the procedure did nothing.

• One neurosurgeon even said, “The placebo effect in brain surgery is not subtle.” 

Asthma & Inhalers

 • People with asthma were given:

     • A real inhaler

     • A fake (placebo) inhaler

     • A sham acupuncture treatment

     • Nothing at all

• Subjectively, they all reported feeling better—but only the real inhaler improved lung function.

• Shows the disconnect between perception and measurable effect, but also how strong that perception can be. 


Surgery Scars & Recovery Time

 

• Some patients recover faster if they believe their surgeon is highly skilled or that they had a “less invasive” surgery, even when that’s not true.

• Healing time sped up, and scar appearance improved—belief influenced cellular repair and inflammation response. 

Fake Sleep

 Participants were told how much REM sleep they got the night before, regardless of what actually happened.

• Those told they had “high-quality” sleep performed better on cognitive tasks, even if they barely slept.

• Just believing they were rested made their brains perform better.

Phantom Limb Pain Helped by Placebo

 • Amputees with phantom limb pain sometimes get relief from fake nerve blockers, or even just visualization techniques.

• In some cases, just watching a mirror image of their existing limb can “trick” the brain into believing the missing limb is still there—and reduce pain 

Placebo Surgery for Back Pain

 •  Some studies did sham spinal procedures, like facet joint denervation (a common back pain surgery), and the placebo groups reported equal or greater relief compared to real procedures.

• Suggests that pain perception is heavily influenced by expectation and belief. 

Cough Syrup with No Active Ingredient

 • In trials of over-the-counter cough medicine, even syrups with no active drugs were effective for many participants.

• The ritual of taking a thick, sweet syrup made people feel like they were getting better. 

Nocebo

 At its core, it’s the power of expectation—when your brain anticipates harm, it can create or intensify symptoms in your body.

• Fear or anxiety → Brain anticipates pain or sickness

• Body releases stress hormones (like cortisol, adrenaline)

• Immune system, digestive system, and pain pathways respond

• You feel real symptoms—even if the trigger is inert 

The Placebo “Overdose”

 • A man in a depression drug trial took 26 sugar pills, thinking he was overdosing on antidepressants.

• He collapsed with dangerously low blood pressure and had to be hospitalized.

• When doctors found out it was a placebo, his symptoms vanished within minutes. 

Statin Side Effects

 

• Many people report muscle pain from statins (cholesterol meds).

• In blinded trials, those who don’t know they’re taking statins report far fewer side effects.

• But once told about the side effects, more people begin to experience them—even when switched to placebo pills. 

Fake Electromagnetic Sensitivity

 

• People who believed they were sensitive to Wi-Fi or EMF reported headaches, nausea, brain fog when exposed.

• In double-blind studies where the EMF source was actually off, they still experienced symptoms.

• Their symptoms were triggered by expectation, not actual EMF exposure. 

Chemotherapy Placebo: Hair Loss

 

Some patients in chemo drug trials who were given a placebo drug reported hair loss—a side effect they expected.

• No active chemotherapy was administered.

Back Pain from Negative MRI Reports

 

Patients shown a concerning MRI (e.g., bulging disc) were more likely to report pain—even if the disc had nothing to do with their symptoms.

• Just seeing something wrong made them feel worse. 

Common Nocebo-Triggered Symptoms

 These show up frequently when people believe something will make them sick:

• Headaches

• Fatigue

• Nausea

• Dizziness

• Muscle pain

• Tingling or numbness

• Sleep trouble

• Anxiety or panic

• Increased pain sensitivity 

Real Biological Changes

 

The nocebo effect isn’t “in your head” in the dismissive way—it causes actual measurable changes, including:

• Increased cortisol (stress hormone)

• More inflammation markers

• Altered brain activity in pain-processing centers

• Reduced levels of endorphins (natural painkillers) 

Where Nocebo Commonly Shows Up

 • Drug side effect warnings (especially long, scary lists)

• Media-induced fear (e.g., vaccine rumors, chemical scares)

• Diagnoses or misdiagnoses

• Negative medical communication (“This might be really painful.”)

• Hypochondria or health anxiety 

How to Protect Yourself

 • Reframe information: Focus on benefits more than risks

• Work with optimistic clinicians: How they deliver news matters

• Don’t Google symptoms obsessively (leads to self-diagnosing and anxiety loops)

• Use mindfulness, CBT, or visualization to redirect negative expectation loops 

Psychological Suggestion and Fatal Outcomes: Verified Cases

Case of “Mr. J” (1979) –

  A 37-year-old German patient exemplified psychogenic death in a medical setting​pubmed.ncbi.nlm.nih.gov. Suffering back pain after spinal surgery, he became convinced the operation had failed. Within a day he shockingly died, even though autopsy and toxicology found no physical cause​pubmed.ncbi.nlm.nih.gov. Researchers concluded he succumbed to a “psychic” trigger – essentially willing himself to die due to hopelessness. This case, published in a 1979 psychosomatic medicine journal, described the patient’s state as total passivity, resignation, and apathy before death​pubmed.ncbi.nlm.nih.gov. It was deemed a classic psychogenic death, where the expectation of doom led to unexplained sudden death. 

“Give-up-itis” in Prisoners of War –

Military psychologists and physicians have long noted a syndrome in extreme trauma survivors (such as POWs or disaster victims) where individuals lose the will to live. Dr. John Leach, who studied this phenomenon, describes “give-up-itis” as a progressive demotivation that can end in death without organic cause​medscape.com. In the Korean War, some captives who remained physically intact nevertheless became withdrawn, refused to eat or move, and died suddenly – a pattern also called psychogenic death. Leach’s research outlines five stages (from social withdrawal to apathy, then aboulia, psychic akinesia, and finally psychogenic death) where a person mentally “switches off” life​medscape.com​medscape.com. In one report, a 19-year-old WWII soldier who lost hope is cited as an example of this fatal surrender​medscape.com. The interpretation by experts is that mental defeat activates a kind of internal shutdown: the brain essentially “accepts death” as a coping mechanism, triggering physiological processes of dying even though the body is otherwise capable​medscape.com. Such cases baffled doctors because no medical reason explains why a previously healthy person would die, underscoring the lethal power of belief and emotional despair​ 

Maori Taboo Death (Cannon 1942) –

 Cannon’s seminal paper describes the case of a Maori woman who accidentally ate fruit from a tapu (taboo) grove​en.wikipedia.org. Upon learning of the transgression, she was overwhelmed by dread at the supernatural punishment she believed would befall her. Less than 24 hours later, she was dead,​en.wikipedia.org despite no injury or poison – a psychosomatic death attributed to extreme fear. Cannon interpreted this as evidence that the belief in having violated a sacred taboo induced mortal terror, triggering physiological shock (collapse of blood pressure, etc.) leading to death​ 

Bone-Pointing Curses (Australia) –

 

  • In Australian Aboriginal culture, the “Kurdaitcha” or sorcerer’s bone-pointing curse was historically feared as a death sentence. Medical observers in the colonial era documented that victims of this ritual would literally will themselves to die. Dr. W. E. Roth, a government surgeon in Queensland in the 1890s, reported seeing victims so convinced they’d been “boned” by an enemy that they lay down and died despite readily available food and water​romolocapuano.com. He personally witnessed “three or four such cases”​romolocapuano.com. Another physician, Dr. J. B. Cleland, recounted a case of a “fine, robust tribesman” who was speared with a bone that had been ritually cursed – the man slowly wasted away and died even though the wound was superficial and showed no infection​romolocapuano.com. Cleland emphasized no ordinary lethal cause was found and poisoning was ruled out, implicating malignant psychic influence as the cause​romolocapuano.com​romolocapuano.com. Anthropologist Herbert Basedow in 1925 vividly described the sequence: when an Aboriginal person realizes he’s been “boned,” he reacts with absolute terror – “His cheeks blanch and his eyes become glassy… he attempts to shriek but the sound chokes in his throat, with only froth at his mouth. His body trembles… he collapses… thereafter he refuses food and withdraws… death is only a matter of a short time without a counter-charm.”​romolocapuano.com​romolocapuano.com. The interpretation of these cases by early observers and by Cannon was that fear itself is lethal: the intense activation (and then exhaustion) of the nervous system – a massive stress response followed by shock – literally shuts down vital functions​en.wikipedia.org. Cannon theorized that adrenaline surge and sympathetic nervous system overdrive, followed by collapse of blood pressure and organ failure, explained these deaths​en.wikipedia.org. Modern researchers concur that extreme stress can provoke fatal arrhythmias or cardiovascular collapse (akin to stress-induced cardiomyopathy or “broken heart syndrome”)​en.wikipedia.org​en.wikipedia.org, lending credence to these early reports. In essence, the victim’s belief in the curse’s power becomes a self-fulfilling prophecy carried out by their own body.
     

Placebo Overdose Case (2007) –

A dramatic clinical case reported in General Hospital Psychiatry illustrates how belief alone can cause dangerous physiological reactions​pubmed.ncbi.nlm.nih.gov. A 26-year-old man in an antidepressant drug trial swallowed 29 capsules in a suicide attempt, believing they were a deadly overdose. In reality, he was in the placebo arm – the pills were inert. Nonetheless, he collapsed with life-threatening hypotension (critically low blood pressure), rapid pulse, and profuse sweating​mondediplo.com. He was rushed to the ER; despite IV fluids, doctors struggled to stabilize him. Only after the trial supervisor revealed that the pills were placebos with no drug did the patient’s condition rapidly reverse – his blood pressure normalized within 15 minutes​mondediplo.com. Interpretation: this was a nocebo-induced crisis – his mind generated severe physical symptoms because he expected an overdose. As researchers Reeves et al. note, the case highlights that nocebo responses “may have significant negative impacts” and can mimic medical emergencies​pubmed.ncbi.nlm.nih.gov. The patient’s belief in harm was potent enough to nearly cause a fatal outcome. 

Trial Side-Effects and “Harmful” Placebos –

Large-scale analyses confirm that nocebo effects are common in clinical trials. A 2018 review of data from over 250,000 trial participants found that 1 in 20 people on placebos dropped out due to serious adverse events – including symptoms as severe as chest pain, gastrointestinal crises, and even some deaths​ox.ac.uk. Nearly half of participants reported milder side effects while on a sugar pill​ox.ac.uk. Of course, if a patient in a study dies while on placebo, the actual cause might be an unrelated health issue; but researchers note that negative expectations and misattribution play a huge role​ox.ac.uk. In other words, people often convince themselves they are ill. The University of Oxford team led by Jeremy Howick concluded that many “strange” placebo harms can be explained by patients’ expecting side effects (the nocebo effect) or blaming normal aches on the trial​ox.ac.uk​ox.ac.uk. For instance, if volunteers are warned a drug may cause stomach pain or fatigue, a significant proportion will report exactly those problems even on placebo​ox.ac.uk. The implication is that caution is needed in how we communicate risks: expectations alone can produce real suffering. 

Belief and Heart Disease Risk (Framingham Study) –

 A long-term epidemiological study provided evidence that beliefs can influence mortality. In the famed Framingham Heart Study, researchers noted that women who believed they were prone to heart disease had nearly 4× the risk of dying in the next decade compared to women with identical cardiac risk profiles who did not hold such fatalistic beliefs​tampabay.com. All women had similar blood pressure, cholesterol, weight, etc., so objectively their risk should have been the same. But those convinced “heart trouble runs in my family, I’ll probably die young” did, in fact, die at a much higher rate​tampabay.com. This nocebo-like effect – essentially a self-fulfilling prophecy – suggests psychological stress and expectation may have contributed to heart attacks or fatal arrhythmias. The study underlines what one CDC scientist called the “negative self-fulfilling prophecy” aspect of nocebo responses​tampabay.com: believing you will get sick can help make it so. 

Allergic Reaction by Suggestion (Ikemi’s Poison Ivy Study, 1960s) –

 

  • A classic experiment in Japan by Dr. Yukio Ikemi proved that the mind’s expectations can override the body’s usual allergic responses. The study involved 57 boys highly allergic to a toxic plant (Japanese lacquer tree, similar to poison ivy)​skeptics.stackexchange.com​skeptics.stackexchange.com. The researchers conducted a blind test: each boy had one forearm rubbed with the poisonous leaf and the other arm rubbed with a harmless leaf – but the boys were told the opposite (the poison was said to be harmless, and the harmless leaf was said to be the irritant)​skeptics.stackexchange.com. The results were astonishing: on the arm that the boys believed was exposed to poison, the majority developed itching, redness, and rashes, even though that arm actually only touched a benign leaf​skeptics.stackexchange.com​skeptics.stackexchange.com. Conversely, the arm that actually had real poison ivy oil on it but which they thought was safe often showed no reaction at all. In one group of 13 particularly sensitive boys, 84.6% reacted strongly to the “harmless” leaf when told it was poison​skeptics.stackexchange.com. Overall, suggestion alone produced some level of rash in up to ~90% of subjects across various conditions​skeptics.stackexchange.com. Medical examination confirmed that these weren’t imaginary complaints – the skin actually erupted with genuine dermatitis, in some cases even showing the histological signs of eczema identical to a true allergic reaction​skeptics.stackexchange.com. Ikemi’s paper concluded that suggestion had a statistically significant effect on triggering allergic skin outbreaks (with p < 0.001)​skeptics.stackexchange.com. In more than half the subjects, belief outweighed physiology – meaning if they expected a rash, they got one, and if they expected to be fine, their bodies suppressed the allergic response​skeptics.stackexchange.com. This controlled study is a striking demonstration of the nocebo/placebo effect: the mind’s expectations can literally produce or prevent allergic inflammation. Researchers interpreted this as evidence that the brain’s influence (through stress or neural mechanisms) can mimic or block immune reactions at the skin level

Fake Electric Shock Experiment (1980s) –

 

  • To test nocebo effects in a laboratory setting, researchers have told volunteers to expect some harmless but unpleasant stimulus and then observed physiological outcomes. In one placebo-controlled trial of pain, healthy volunteers were informed that a mild electric current would be passed through their heads (to study headaches), though in reality no current was delivered. Nonetheless, approximately two-thirds of the subjects reported developing a headache purely from the power of suggestion​tampabay.com. They experienced real pain symptoms despite nothing physically causing them. This “imaginary shock” study, reported by nocebo researchers, underscores how simply expecting a symptom can manifest it. The participants weren’t malingering; their headaches were real to them – a direct result of the induced anxiety and expectation. The study’s interpretation was that negative expectation can induce measurable symptoms (a “meaning response” in the words of anthropologist Daniel Moerman)​tampabay.com, demonstrating a controlled nocebo effect on a common sensation like pain.


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Man’s greatest prison is unquestioned belief.

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